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The results from Paradromics reported on September 14, 2026, have not been peer-reviewed or published in a journal.
Paradromics' CSO Vikash Gilja stated the BCI system worked equally well when the patient whispered.
Dr. Edward Chang's lab and other researchers have previously enabled patients to produce spontaneous speech using brain-computer interfaces.
Much previous BCI research required patients to be connected to a computer via a cable attached to a port in their head.
Dr. Edward Chang is the chairman of neurological surgery at UCSF, is not involved in the Paradromics trial, and his lab has pioneered BCI technology.
Dr. William Marks stated the Paradromics clinical trial will enroll 10 patients with disorders causing speech and limb paralysis, like stroke and ALS.
The first patient in the Paradromics trial was implanted with the Connexus B.C.I. system, containing over 400 electrodes, in June at University of Michigan Health.
The Paradromics brain-computer interface system is wireless and does not require a cord to connect to a computer.
A 68-year-old Michigan woman with limited speaking ability used the Paradromics device for spontaneous conversations, including phone calls.
The first patient in the Paradromics trial has primary lateral sclerosis.
Paradromics announced its brain implant enabled a patient with a paralyzing disorder to converse in real time by decoding imagined speech.
Dr. Siddiqi said that as people get older, balance and mobility exercises are especially important for reducing fall risk.
Dr. Hurst said giving the body time to rest between exercises and in the days afterward is crucial for avoiding overtraining with age.
Weight-bearing exercise can help maintain bone density and protect against fractures.
Kelyssa Hall said adults over 65 should aim for the same exercise guidelines as other adults, as much as their medical history allows.
The American College of Sports Medicine recommends adults get 150 minutes of moderate-intensity aerobic exercise and two muscle-strengthening sessions weekly.
Older adults can have a reduced thirst response compared to when they were younger.
Older adults lose more fast-twitch muscle fibers (for force and power) than slow-twitch muscle fibers (for endurance).
Chronic inflammation, which scientists call 'inflammaging', can increase with age and could impede muscle regeneration.
Kelyssa Hall stated that as people age, their muscles become less efficient at using protein, and advised consuming protein throughout the day.